The effect of Captopril on benign and malignant reactions in irradiated rat skin.

@article{Ward1990TheEO,
  title={The effect of Captopril on benign and malignant reactions in irradiated rat skin.},
  author={William F. Ward and Agostino Molteni and Chung hsin Ts'ao and Joann M. Hinz},
  journal={The British journal of radiology},
  year={1990},
  volume={63 749},
  pages={
          349-54
        }
}
The effect of the angiotensin converting enzyme inhibitor Captopril on the severity of radiation-induced epilation and moist desquamation and the incidence of skin tumours was determined for up to 52 weeks in male rats. The irradiation consisted of a range of single doses (0, 10, 20, 30 Gy) of 60Co gamma rays to a 3.5 cm2 right hemithorax port. Half of each radiation dose group consumed control powdered chow, and half consumed chow containing Captopril (50 mg/kg/day) continuously after… Expand
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