The effect of CSE gene deletion in caerulein-induced acute pancreatitis in the mouse.

@article{Ang2013TheEO,
  title={The effect of CSE gene deletion in caerulein-induced acute pancreatitis in the mouse.},
  author={Abel Damien Ang and Jack Rivers-Auty and Akhil Hegde and Isao Ishii and Madhav Bhatia},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2013},
  volume={305 10},
  pages={G712-21}
}
Hydrogen sulfide (H2S) has been reported to be involved in the signaling of the inflammatory response; however, there are differing views as to whether it is pro- or anti-inflammatory. In this study, we sought to determine whether endogenously synthesized H2S via cystathionine-γ-lyase (CSE) plays a pro- or anti-inflammatory role in caerulein-induced pancreatitis. To investigate this, we used mice genetically deficient in CSE to elucidate the function of CSE in caerulein-induced acute… CONTINUE READING

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