The effect of CO2 and non-CO2-generating buffers on cerebral acidosis after cardiac arrest: A 31P NMR study.

@article{Rosenberg1989TheEO,
  title={The effect of CO2 and non-CO2-generating buffers on cerebral acidosis after cardiac arrest: A 31P NMR study.},
  author={Jack M. Rosenberg and Gerard B. Martin and N. Paradis and Richard Michael Nowak and David Walton and Tony Appleton and Kenneth Michael A Welch},
  journal={Annals of emergency medicine},
  year={1989},
  volume={18 4},
  pages={341-7}
}
There is controversy regarding the use of alkalinizing agents during reperfusion after cardiac arrest. The potential deleterious effects of sodium bicarbonate (bicarb) administration, including paradoxic cerebral acidosis, have led to the search for alternative agents. Tromethamine (tris) is a non-CO2-generating buffer that has been proposed for use during… CONTINUE READING