The effect of Bacille Calmette-Guérin on the evolution of new enhancing lesions to hypointense T1 lesions in relapsing remitting MS

@article{Paolillo2003TheEO,
  title={The effect of Bacille Calmette-Gu{\'e}rin on the evolution of new enhancing lesions to hypointense T1 lesions in relapsing remitting MS},
  author={Andrea Paolillo and Maria Gabriella Buzzi and Elisabetta Giugni and Umberto Sabatini and Stefano Bastianello and Carlo Pozzilli and Marco Salvetti and Giovanni Ristori},
  journal={Journal of Neurology},
  year={2003},
  volume={250},
  pages={247-248}
}
Sirs: A recent crossover trial documented that a single Bacille Calmette-Guérin (BCG) vaccination decreased the disease activity on magnetic resonance imaging (MRI) in a cohort of 12 relapsingremitting multiple sclerosis (RRMS) patients [1]. A reduction in MRI disease activity is an expression of the influence of the drug on the inflammatory component of the disease. However, this does not necessarily imply an effect on tissue damage. Hence, there is a need for testing the effect of new… CONTINUE READING
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Lesion heterogeneity in MS: a study of the relationships between appearance on T1-weighted images, T1 relaxation times and metabolite concentrations

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