The effect of BMP-2 on the osteoconductive properties of β-tricalcium phosphate in rat calvaria defects.

@article{Luvizuto2011TheEO,
  title={The effect of BMP-2 on the osteoconductive properties of β-tricalcium phosphate in rat calvaria defects.},
  author={Elo{\'a} Rodrigues Luvizuto and Stefan Tangl and Gerald Zanoni and Tetuo Okamoto and Celso K Sonoda and Reinhard Gruber and Roberta Okamoto},
  journal={Biomaterials},
  year={2011},
  volume={32 15},
  pages={
          3855-61
        }
}
Bone formation in critical-sized calvaria defects is strongly dependent on the osteoconductive properties of grafts. It remains a matter of controversy whether biomaterials can replace autografts and whether the supplementation of biomaterials with Bone Morphogenetic Proteins (BMPs) is necessary to enhance bone formation. We examined rat calvaria critical-sized defects (5-mm-diameter) treated with β-tricalcium phosphate (TCP; Cerasorb® M), polylactic and polyglycolic acid gel (PLA/PGA… CONTINUE READING
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