The effect of 4 wk of oral echinacea supplementation on serum erythropoietin and indices of erythropoietic status.
@article{Whitehead2007TheEO,
title={The effect of 4 wk of oral echinacea supplementation on serum erythropoietin and indices of erythropoietic status.},
author={Malcolm T. Whitehead and Tyler D. Martin and Timothy Paul Scheett and Michael J. Webster},
journal={International journal of sport nutrition and exercise metabolism},
year={2007},
volume={17 4},
pages={
378-90
}
}The purpose of this investigation was to determine whether echinacea supplementation results in alterations of erythroid growth factors and erythropoietic status. Twenty-four men age 24.9 +/- 4.2 y, height 1.7 +/- 0.8 m, weight 87.9 +/- 14.6 kg, and 19.3% +/- 6.5% body fat were grouped using a double-blind design and self- administered an 8000-mg/d dose of either echinacea (ECH) or placebo (PLA) in 5 x 400 mg x 4 times/d for 28 d. Blood samples were collected and analyzed for red blood cells…
18 Citations
Six weeks of oral Echinacea purpurea supplementation does not enhance the production of serum erythropoietin or erythropoietic status in recreationally active males with above-average aerobic fitness.
- MedicineApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
- 2019
It is indicated that 6 weeks of oral E. purpurea supplementation in recreationally active males with above average aerobic fitness did not enhance EPO or erythropoietic status, and these findings are in contrast with previous reports of E. Purpurea supplements in untrained participants with average fitness levels, but consistent with observations in trained endurance athletes.
Running Economy and Maximal Oxygen Consumption After 4 Weeks of Oral Echinacea Supplementation
- MedicineJournal of strength and conditioning research
- 2012
The data suggest that ECH supplementation results in significant increases in EPO, V[Combining Dot Above]O2max, and running economy, which is consistent with previous studies of Echinacea supplementation.
EFFECT OF ECHINACEA EXTRACT SUPPLEMENTATION ON GROWTH PERFORMANCE AND HEMO-BIOCHEMICAL TRAITS OF GROWING RABBITS
- Biology
- 2008
The results indicate that treatment of growing rabbits with Echinacea extract in different doses improved growth performance, stimulates immune functions and protein metabolism without harmful effects on liver and kidney functions.
Echinacea-Based Dietary Supplement Does Not Increase Maximal Aerobic Capacity in Endurance-Trained Men and Women
- MedicineJournal of dietary supplements
- 2016
This echinacea-based dietary supplement provided at two different doses would increase erythropoietin (EPO) and other blood markers involved in improving aerobic capacity and maximal oxygen consumption (VO2max) in endurance-trained men and women should not be recommended as a means to improve performance in endurance athletes.
Rabbit dietary supplementation with pale purple coneflower. 1. Effects on the reproductive performance and immune parameters of does.
- BiologyAnimal : an international journal of animal bioscience
- 2016
No impacts of EPAL have been observed on the reproductive or haematological parameters of the does, and the effects of dietary supplementation with EPAL on the performances, bacterial community, blood parameters and immunity in growing rabbits are reported.
The Use of Echinacea to Improve Oxygen Transport Capacity
- Biology
- 2011
An increase in oxygen transport capacity with Echinacea supplementation may provide a therapeutic means by which to diminish the adverse effects caused by a decrease in oxygen availability and enhance endurance exercise performance through the same mechanism.
Echinacea supplementation: does it really improve aerobic fitness?
- Biology, MedicineJournal of exercise nutrition & biochemistry
- 2016
The published literature does not support the use of Echinacea as an ergogenic aid to improve aerobic fitness in healthy untrained or trained subjects.
Human blood mononuclear cell in vitro cytokine response before and after two different strenuous exercise bouts in the presence of bloodroot and Echinacea extracts.
- BiologyBlood cells, molecules & diseases
- 2009
A systematic review on the effects of Echinacea supplementation on cytokine levels: Is there a role in COVID-19?
- Medicine, BiologyMetabolism Open
- 2021
The effect of Echinacea spp. on the prevention or treatment of COVID-19 and other respiratory tract infections in humans: A rapid review
- BiologyAdvances in Integrative Medicine
- 2020
References
SHOWING 1-10 OF 38 REFERENCES
Immunological and haematinic consequences of feeding a standardised Echinacea (Echinacea angustifolia) extract to healthy horses.
- MedicineEquine veterinary journal
- 2002
It was concluded that Echinacea effectively stimulates equine immunocompetence, and the plant extract behaves, in equine subjects, as a haematinic agent, i.e. one which improves the quality of blood by increasing haemoglobin levels and the number of erythrocytes and which is considered to improve parameters of exercise physiology and performance.
Alkylamides of Echinacea purpurea stimulate alveolar macrophage function in normal rats.
- BiologyInternational immunopharmacology
- 2002
Effect of enhanced erythropoiesis on iron absorption.
- MedicineThe Journal of laboratory and clinical medicine
- 1992
It is concluded that the striking enhancement of iron absorption following regular erythropoietin administration in normal subjects is related to the combined effect of diminished iron stores and augmented eryththropoiesis.
Antioxidant and immuno-enhancing effects of Echinacea purpurea.
- Biology, MedicineBiological & pharmaceutical bulletin
- 2004
We studied the protective effects of Echinacea purpurea against radiation by evaluating changes in the peripheral blood cell count and peripheral blood antioxidant activity. E. purpurea…
Control of Erythropoietin Production 1
- Biology, MedicineProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
- 1983
The mechanism for the control of kidney production of erythropoietin is not well understood but is postulated to be regulated by the oxygen level in a critical renal sensor cell, and has been the subject of several investigations and reviews.
Erythropoietin: Physiologic and Pharmacologic Aspects
- Medicine, BiologyProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
- 1997
It has been postulated that Epo decreases the rate which Epo-dependent progenitor cells undergo programed cell death (apoptosis), and there are two major signal transduction pathways activated by the Epo receptor: the JAK2-STAT5 pathway and the ras pathway.
A clinical trial of prostaglandin E2 to increase erythropoiesis in anemia of end stage renal disease. A preliminary report.
- MedicineProstaglandins, leukotrienes, and medicine
- 1984
Echinacea-induced cytokine production by human macrophages.
- BiologyInternational journal of immunopharmacology
- 1997
Immunopharmacological activity of Echinacea preparations following simulated digestion on murine macrophages and human peripheral blood mononuclear cells
- BiologyJournal of leukocyte biology
- 2000
Echinacea herb and root powders were found to stimulate murine macrophage cytokine secretion as well as to significantly enhance the viability and/or proliferation of human PBMCs in vitro.
Erythropoietin, iron, and erythropoiesis.
- MedicineBlood
- 2000
Newer measurements of erythrocyte and reticulocyte indices using automated counters show promise in the evaluation of iron-restricted erythropoiesis, suggesting traditional biochemical markers of storage iron in patients with anemia caused by chronic disease are unhelpful in the assessment of iron status.






