The effect of 2,3-diphosphoglycerate on the solubility of deoxyhemoglobin S.

Abstract

Although highly charged polyanions, such as inositol hexaphosphate, have been clearly shown to decrease the solubility of deoxyhemoglobin S, the effect of 2,3-diphosphoglycerate (DPG), the endogenous allosteric effector within the red cell, has been more controversial. In this work we have compared the effect of DPG on the solubility of native… (More)

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@article{Poillon1986TheEO, title={The effect of 2,3-diphosphoglycerate on the solubility of deoxyhemoglobin S.}, author={William N. Poillon and B C Kim and Emily Welty and Joseph A Walder}, journal={Archives of biochemistry and biophysics}, year={1986}, volume={249 2}, pages={301-5} }