The ectopic expression of the gastric inhibitory polypeptide receptor is frequent in adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia, but rare in unilateral tumors.

@article{Groussin2002TheEE,
  title={The ectopic expression of the gastric inhibitory polypeptide receptor is frequent in adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia, but rare in unilateral tumors.},
  author={Lionel Groussin and Karine Perlemoine and Vincent Contesse and Herv{\'e} Pierre Lefebvre and Antoine Tabarin and Philippe Thi{\'e}blot and Jean Louis Schlienger and Jean Pierre Luton and Xavier Y Bertagna and J{\'e}r{\^o}me Bertherat},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2002},
  volume={87 5},
  pages={
          1980-5
        }
}
Control of cortisol secretion by the abnormal expression of the gastric inhibitory polypeptide receptor (GIP-R) have been observed in some rare cases of ACTH-independent, food-dependent Cushing's syndrome (FD-ACS) due to adrenal adenoma (AA) or bilateral macronodular hyperplasia (AIMAH). This study was performed to determine the prevalence of GIP-R ectopic expression in ACS and its correlation with fasting cortisol levels. GIP-R expression was studied by RT-PCR in 30 unilateral adrenal tumors… CONTINUE READING

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Pathogenesis of benign adrenocortical tumors.

Best practice & research. Clinical endocrinology & metabolism • 2010

ACTH-independent macronodular adrenal hyperplasia.

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