The early gene product EUO is a transcriptional repressor that selectively regulates promoters of Chlamydia late genes.

@article{Rosario2012TheEG,
  title={The early gene product EUO is a transcriptional repressor that selectively regulates promoters of Chlamydia late genes.},
  author={Christopher J Rosario and Ming Tan},
  journal={Molecular microbiology},
  year={2012},
  volume={84 6},
  pages={1097-107}
}
The obligate intracellular bacterium Chlamydia has an unusual developmental cycle in which there is conversion between two forms that are specialized for either intracellular replication or propagation of the infection to a new host cell. Expression of late chlamydial genes is upregulated during conversion from the replicating to the infectious form, but the mechanism for this temporal regulation is unknown. We found that EUO, which is expressed from an early gene, binds to two sites upstream… CONTINUE READING
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