The early effects of chronic hypoxia on the cardiovascular system in the rat: role of nitric oxide

@article{Walsh2006TheEE,
  title={The early effects of chronic hypoxia on the cardiovascular system in the rat: role of nitric oxide},
  author={M. P. Walsh and J. Marshall},
  journal={The Journal of Physiology},
  year={2006},
  volume={575}
}
  • M. P. Walsh, J. Marshall
  • Published 2006
  • Medicine
  • The Journal of Physiology
  • Experiments were performed under Saffan anaesthesia on normoxic (N) rats and on chronically hypoxic rats exposed to 12% O2 for 1, 3 or 7 days (1, 3 or 7CH rats): N rats routinely breathed 21% O2 and CH rats 12% O2. The 1, 3 and 7CH rats showed resting hyperventilation relative to N rats, but baseline heart rate (HR) was unchanged and arterial blood pressure (ABP) was lowered. Femoral vascular conductance (FVC) was increased in 1 and 3CH rats, but not 7CH rats. When 1–7CH rats were acutely… CONTINUE READING
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