The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.

@article{Rmrand2009TheEA,
  title={The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.},
  author={Francis R{\'e}m{\'e}rand and Charlotte Le Tendre and Annick Baud and Claude Couvret and Xavier J L Pourrat and Luc Favard and Marc Laffon and Jacques Fusciardi},
  journal={Anesthesia and analgesia},
  year={2009},
  volume={109 6},
  pages={1963-71}
}
BACKGROUND Ketamine has been shown to have a morphine-sparing effect soon after surgery. Nevertheless, whether this effect still exists after being combined with nonsteroidal antiinflammatory drugs and acetaminophen, and whether ketamine can decrease chronic pain after nononcologic surgery remain unclear. Thus, we designed a study to assess ketamine's effect on acute and chronic postoperative pain when combined with multimodal analgesia after total hip arthroplasty (THA). METHODS Patients… CONTINUE READING