The e3 ubiquitin ligase gene family in plants: regulation by degradation.

  title={The e3 ubiquitin ligase gene family in plants: regulation by degradation.},
  author={Elisabetta Mazzucotelli and Sara Belloni and Daniela Marone and Am De Leonardis and Davide Guerra and Natale Di Fonzo and Luigi Cattivelli and Am Mastrangelo},
  journal={Current genomics},
  volume={7 8},
The regulation of protein expression and activity has been for long time considered only in terms of transcription/translation efficiency. In the last years, the discovery of post-transcriptional and post-translational regulation mechanisms pointed out that the key factor in determining transcript/protein amount is the synthesis/degradation ratio, together with post-translational modifications of proteins. Polyubiquitinaytion marks target proteins directed to degradation mediated by 26S… CONTINUE READING

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