The e (P4) outer membrane protein of Haemophilus influenzae: biologic activity of anti-e serum and cloning and sequencing of the structural gene.

@article{Green1991TheE,
  title={The e (P4) outer membrane protein of Haemophilus influenzae: biologic activity of anti-e serum and cloning and sequencing of the structural gene.},
  author={Bruce Andrew Green and J E Farley and T Quinn-Dey and Robert A. Deich and Gary W Zlotnick},
  journal={Infection and immunity},
  year={1991},
  volume={59 9},
  pages={3191-8}
}
Outer membrane proteins of nontypeable (NT) Haemophilus influenzae are among the major candidates for inclusion in vaccines against these organisms. This article reports the purification of the e (P4) lipoprotein of H. influenzae and the subsequent production of antiserum directed against this protein. The anti-e polyclonal serum cross-reacted with e protein in multiple clinical NT H. influenzae isolates. Monoclonal antibody analysis of e protein showed at least one surface-exposed epitope to… CONTINUE READING
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