The dynein heavy chain family.

@article{Asai2004TheDH,
  title={The dynein heavy chain family.},
  author={David J. Asai and David E. Wilkes},
  journal={The Journal of eukaryotic microbiology},
  year={2004},
  volume={51 1},
  pages={23-9}
}
Dynein is the large molecular motor that translocates to the (-) ends of microtubules. Dynein was first isolated from Tetrahymena cilia four decades ago. The analysis of the primary structure of the dynein heavy chain and the discovery that many organisms express multiple dynein heavy chains have led to two insights. One, dynein, whose motor domain comprises six AAA modules and two potential mechanical levers, generates movement by a mechanism that is fundamentally different than that which… CONTINUE READING

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