The dynamics of engineered resident proteins in the mammalian Golgi complex relies on cisternal maturation

@inproceedings{Rizzo2013TheDO,
  title={The dynamics of engineered resident proteins in the mammalian Golgi complex relies on cisternal maturation},
  author={Riccardo Rizzo and Seetharaman Parashuraman and Peppino Mirabelli and Claudia Puri and John Milton Lucocq and Alberto Luini},
  booktitle={The Journal of cell biology},
  year={2013}
}
After leaving the endoplasmic reticulum, secretory proteins traverse several membranous transport compartments before reaching their destinations. How they move through the Golgi complex, a major secretory station composed of stacks of membranous cisternae, is a central yet unsettled issue in membrane biology. Two classes of mechanisms have been proposed. One is based on cargo-laden carriers hopping across stable cisternae and the other on "maturing" cisternae that carry cargo forward while… CONTINUE READING