The dynamics of cancer chromosomes and genomes

  title={The dynamics of cancer chromosomes and genomes},
  author={Christine J. Ye and G. Liu and Steven W. Bremer and Henry H. Q. Heng},
  journal={Cytogenetic and Genome Research},
  pages={237 - 246}
  • C. YeG. Liu H. Heng
  • Published 1 November 2007
  • Biology
  • Cytogenetic and Genome Research
A key feature of cancer chromosomes and genomes is their high level of dynamics and the ability to constantly evolve. This unique characteristic forms the basis of genetic heterogeneity necessary for cancer formation, which presents major obstacles to current cancer diagnosis and treatment. It has been difficult to integrate such dynamics into traditional models of cancer progression. In this conceptual piece, we briefly discuss some of the recent exciting progress in the field of cancer… 

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