The dynamics of GABA signaling: Revelations from the circadian pacemaker in the suprachiasmatic nucleus.

@article{Albers2017TheDO,
  title={The dynamics of GABA signaling: Revelations from the circadian pacemaker in the suprachiasmatic nucleus.},
  author={H Elliott Albers and James C Walton and Karen L Gamble and John K McNeill and Daniel Hummer},
  journal={Frontiers in neuroendocrinology},
  year={2017},
  volume={44},
  pages={35-82}
}
Virtually every neuron within the suprachiasmatic nucleus (SCN) communicates via GABAergic signaling. The extracellular levels of GABA within the SCN are determined by a complex interaction of synthesis and transport, as well as synaptic and non-synaptic release. The response to GABA is mediated by GABAA receptors that respond to both phasic and tonic GABA release and that can produce excitatory as well as inhibitory cellular responses. GABA also influences circadian control through the… CONTINUE READING
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