The dynamic control of kiss-and-run and vesicular reuse probed with single nanoparticles.

@article{Zhang2009TheDC,
  title={The dynamic control of kiss-and-run and vesicular reuse probed with single nanoparticles.},
  author={Qi Zhang and Yulong Li and Richard W. Tsien},
  journal={Science},
  year={2009},
  volume={323 5920},
  pages={1448-53}
}
Vesicular secretion of neurotransmitter is essential for neuronal communication. Kiss-and-run is a mode of membrane fusion and retrieval without the full collapse of the vesicle into the plasma membrane and de novo regeneration. The importance of kiss-and-run during efficient neurotransmission has remained in doubt. We developed an approach for loading individual synaptic vesicles with single quantum dots. Their size and pH-dependent photoluminescence change allowed us to distinguish kiss-and… CONTINUE READING
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