The dynamic changes of zinc transporter 8 autoantibodies in Czech children from the onset of Type 1 diabetes mellitus

@article{Petruelkov2014TheDC,
  title={The dynamic changes of zinc transporter 8 autoantibodies in Czech children from the onset of Type 1 diabetes mellitus},
  author={Lenka Petru{\vz}elkov{\'a} and Rossitza Ananieva-Jordanova and Jana V{\vc}el{\'a}kov{\'a} and Z. Vesel{\'y} and Katerina Stechov{\'a} and Jan Lebl and Petra Dusatkova and Zdeněk {\vS}umn{\'i}k and Rebecca L Coles and Michael Powell and Jadwiga Furmaniak and Bernard Rees Smith and Stanislava Kolou{\vs}kov{\'a}},
  journal={Diabetic Medicine},
  year={2014},
  volume={31},
  pages={165 - 171}
}
The prevalence of autoantibodies to zinc transporter 8 (ZnT8) in Czech children at the onset of Type 1 diabetes mellitus and dynamic changes in ZnT8 autoantibody levels during disease progression were studied. The value of ZnT8 autoantibody measurements in diagnosis of Type 1 diabetes was assessed. 
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TLDR
ZnT8A prevalence in children with T1D in Turkey was compatible with the literature and the ratio of patients who are clinically considered to have T 1D but have negative routine diabetes auto-antibodies were observed to decrease nearly by 50% when ZnT 8 antibodies were added to the panel.
Anti-zinc transporter protein 8 autoantibodies significantly improve the diagnostic approach to type 1 diabetes: an Italian multicentre study on paediatric patients
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Zinc transporter 8 (ZnT8) autoantibody prevalence in black South African participants with type 1 diabetes
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The presence of ZnT8 autoantibody positivity was not related to a younger age at diagnosis in black South African patients with type 1 diabetes, however, the greater the numbers ofAutoantibodies present in an individual the earlier the age at diagnosed.
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When ZnT8A-positive and -negative T1D cases were compared, no differences were detected in age at diagnosis, duration of diabetes, presence of ketoacidosis, body mass index, glycosylated hemoglobin concentration, or C-peptide concentrations.
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Znt8ab prevalence in children with T1D in Turkey was compatible with the data from most countries, and the ratio of patients who are clinically considered to have type 1 diabetes but have negative routine diabetes auto-antibodies were observed to decrease nearly by 50% when ZNT8 was added to the panel.
Bridging-type enzyme-linked immunoassay for zinc transporter 8 autoantibody measurements in adult patients with diabetes mellitus.
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TLDR
This study determined whether the presence of pancreatic autoantibodies (GADA, IA‐2A, anti‐ZnT8, or ICA) was associated with serious complications or concomitant diseases of adult patients diagnosed with T2D.
Temporal dynamics of serum let‐7g expression mirror the decline of residual beta‐cell function in longitudinal observation of children with type 1 diabetes
In type 1 diabetes mellitus (T1DM), the introduction of insulin is typically followed by a brief remission period, with subsequent gradual decline in beta‐cell function. Several studies described…
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TLDR
Diabetes-associated autoantibodies including ZnT8Ab were found in children and adolescents with GD and HT and the association of AITDs and T1DM at the serological level was assessed.
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Screening for non-diabetes Ab in T1DM may be helpful in identifying subclinical cases of autoimmune thyroid, celiac or Addison’s disease (AD) in Polish children with type 1 diabetes mellitus.
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