The dynamic DNA methylation cycle from egg to sperm in the honey bee Apis mellifera.

@article{Drewell2014TheDD,
  title={The dynamic DNA methylation cycle from egg to sperm in the honey bee Apis mellifera.},
  author={Robert A. Drewell and Eliot Bush and Emily J Remnant and Garrett T. Wong and Suzannah M. Beeler and Jessica L. Stringham and Julianne Lim and Benjamin P. Oldroyd},
  journal={Development},
  year={2014},
  volume={141 13},
  pages={2702-11}
}
In honey bees (Apis mellifera), the epigenetic mark of DNA methylation is central to the developmental regulation of caste differentiation, but may also be involved in additional biological functions. In this study, we examine the whole genome methylation profiles of three stages of the haploid honey bee genome: unfertilised eggs, the adult drones that develop from these eggs and the sperm produced by these drones. These methylomes reveal distinct patterns of methylation. Eggs and sperm show… CONTINUE READING
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