The durations of hippocampal and cortical cholinergic activation induced by spatial discrimination testing of mice in an eight-arm radial maze decrease as a function of acquisition.

@article{Toumane1989TheDO,
  title={The durations of hippocampal and cortical cholinergic activation induced by spatial discrimination testing of mice in an eight-arm radial maze decrease as a function of acquisition.},
  author={Abdoulaye Toumane and Thomas Durkin and Aline Marighetto and Robert Jaffard},
  journal={Behavioral and neural biology},
  year={1989},
  volume={52 2},
  pages={
          279-84
        }
}
Sodium-dependent high-affinity choline uptake velocities in P2 fractions of the hippocampus and cortex of mice were analyzed at different times following both the first (Day 1) and last (Day 9) daily sessions of a spatial discrimination testing procedure in an eight-arm radial maze. Results showed that the immediate (30 s) post-training increase in mean hippocampal and cortical cholinergic activity observed on Day 1 did not significantly vary over days despite a marked and progressive… CONTINUE READING

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