The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells.

Abstract

The impact of exposure to Ag on the development and maintenance of human CD4(+) memory T cells in general and HIV infection in particular is partially understood. In this study, we measured HIV-specific CD4(+) T cell proliferative responses against HIV proteins and derived peptides one year after highly active antiretroviral therapy initiation in 39 HIV… (More)

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