The dual role of lipopolysaccharide as effector and target molecule.

  title={The dual role of lipopolysaccharide as effector and target molecule.},
  author={Andre Wiese and Klaus Brandenburg and Artur J. Ulmer and Ulrich Seydel and Sven M{\"u}ller-Loennies},
  journal={Biological chemistry},
  volume={380 7-8},
Lipopolysaccharides (LPS) are major integral components of the outer membrane of Gram-negative bacteria being exclusively located in its outer leaflet facing the bacterial environment. Chemically they consist in different bacterial strains of a highly variable O-specific chain, a less variable core oligosaccharide, and a lipid component, termed lipid A, with low structural variability. LPS participate in the physiological membrane functions and are, therefore, essential for bacterial growth and… CONTINUE READING
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