The dual nature of neurotrophins.

  title={The dual nature of neurotrophins.},
  author={R{\"u}diger Schweigreiter},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  volume={28 6},
Neurotrophins are a small family of dimeric secretory proteins in vertebrate neurons with a broad spectrum of functions. They are generated as pro-proteins with a functionality that is distinct from the proteolytically processed form. The cellular responses of neurotrophins are mediated by three different types of receptor proteins, the receptor tyrosine kinases of the Trk family, the neurotrophin receptor p75(NTR), which is a member of the tumor necrosis factor receptor (TNFR) superfamily, and… CONTINUE READING

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