The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens.

@article{Chan2015TheDG,
  title={The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens.},
  author={Ting Fung Chan and Kun-mei Ji and Aldrin Kay-Yuen Yim and Xiao-Yu Liu and Jun-wei Zhou and R Q Li and Kevin Yi Yang and Jing Li and Meng Li and Patrick Tik-Wan Law and Yu-lan Wu and Ze-Lang Cai and Hao Qin and Ying Bao and Ross Ka-kit Leung and Patrick Kwok-Shing Ng and Ju Zou and Xiao-Jun Zhong and Pi-xin Ran and Nan-shan Zhong and Zhigang Liu and Stephen Kwok-Wing Tsui},
  journal={The Journal of allergy and clinical immunology},
  year={2015},
  volume={135 2},
  pages={539-48}
}
BACKGROUND A sequenced house dust mite (HDM) genome would advance our understanding of HDM allergens, a common cause of human allergies. OBJECTIVE We sought to produce an annotated Dermatophagoides farinae draft genome and develop a combined genomic-transcriptomic-proteomic approach for elucidation of HDM allergens. METHODS A D farinae draft genome and transcriptome were assembled with high-throughput sequencing, accommodating microbiome sequences. The allergen gene structures were… CONTINUE READING
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