The downregulation of miR‑125a‑5p functions as a tumor suppressor by directly targeting MMP‑11 in osteosarcoma.

@article{Waresijiang2016TheDO,
  title={The downregulation of miR‑125a‑5p functions as a tumor suppressor by directly targeting MMP‑11 in osteosarcoma.},
  author={Niyazi Waresijiang and Jungang Sun and Rewuti Abuduaini and Tayier Jiang and Wenzheng Zhou and Hong Yuan},
  journal={Molecular medicine reports},
  year={2016},
  volume={13 6},
  pages={4859-64}
}
Osteosarcoma is one of the most common primary malignant bone cancers in juveniles and adults. Increasingly, reports indicate that microRNAs (miRNAs) may provide novel therapeutic targets for cancer treatment. The aim of the present study was to investigate the expression of miR‑125a‑5p and to identify its functional significance in osteosarcoma. This… CONTINUE READING