The double face of the histone variant H3.3

@article{Szenker2011TheDF,
  title={The double face of the histone variant H3.3},
  author={Emmanuelle Szenker and Dominique Ray-Gallet and Genevi{\`e}ve Almouzni},
  journal={Cell Research},
  year={2011},
  volume={21},
  pages={421-434}
}
Histone proteins wrap DNA to form nucleosome particles that compact eukaryotic genomes while still allowing access for cellular processes such as transcription, replication and DNA repair. Histones exist as different variants that have evolved crucial roles in specialized functions in addition to their fundamental role in packaging DNA. H3.3 – a conserved histone variant that is structurally very close to the canonical histone H3 – has been associated with active transcription. Furthermore, its… CONTINUE READING

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