The dorsal tegmental noradrenergic projection: an analysis of its role in maze learning.

@article{Roberts1976TheDT,
  title={The dorsal tegmental noradrenergic projection: an analysis of its role in maze learning.},
  author={Darryn C Roberts and M. T. Price and H. Christian Fibiger},
  journal={Journal of comparative and physiological psychology},
  year={1976},
  volume={90 4},
  pages={363-72}
}
The hypothesis that the noradrenergic projection from the locus coeruleus (LC) to the cerebral cortex and hippocampus is an important neural substrate for learning was evaluated. Maze performance was studied in rats receiving either electrolytic lesions of LC or 6-hydroxydopamine (6-OHDA) lesions of the dorsal tegmental noradrenergic projection. The LC lesions did not disrupt the acquisition of a running response for food reinforcement in an L-shaped runway, even though hippocampal-cortical… CONTINUE READING

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