The dorsal raphe nucleus is integral to negative prediction errors in Pavlovian fear.

@article{Berg2014TheDR,
  title={The dorsal raphe nucleus is integral to negative prediction errors in Pavlovian fear.},
  author={Benjamin A. Berg and Geoffrey Schoenbaum and Michael A McDannald},
  journal={The European journal of neuroscience},
  year={2014},
  volume={40 7},
  pages={3096-101}
}
Prediction errors are central to modern learning theories. While brain regions contributing to reward prediction errors have been uncovered, the sources of aversive prediction errors remain largely unknown. Here we used probabilistic and deterministic reinforcement procedures, followed by extinction, to examine the contribution of the dorsal raphe nucleus to negative, aversive prediction errors in Pavlovian fear. Rats with dorsal raphe lesions were able to acquire fear and reduce fear to a non… CONTINUE READING
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