The dopamine receptor D1 gene is associated with the length of interval between first heroin use and onset of dependence in Chinese Han heroin addicts

@article{Peng2013TheDR,
  title={The dopamine receptor D1 gene is associated with the length of interval between first heroin use and onset of dependence in Chinese Han heroin addicts},
  author={Sufang Peng and Jiang Du and Haifeng Jiang and Yingmei Fu and Hanhui Chen and Haiming Sun and Dongxiang Wang and Shunying Yu and Min Zhao},
  journal={Journal of Neural Transmission},
  year={2013},
  volume={120},
  pages={1591-1598}
}
Previous researches showed that the dopamine receptor D1 (DRD1) may play a critical role in drug dependence. This research aimed to determine whether DRD1 played a role in development of heroin dependence in Chinese heroin-dependent patients. 465 Chinese Han heroin-dependent subjects and 379 healthy controls were recruited in the Shanghai region. Five single-nucleotide-polymorphisms (SNPs) of the DRD1 gene were genotyped in all subjects. The results found that the frequencies of DRD1 SNP… CONTINUE READING