The dopamine D3/D2 receptor agonist 7-OH-DPAT induces cognitive impairment in the marmoset.

@article{Smith1999TheDD,
  title={The dopamine D3/D2 receptor agonist 7-OH-DPAT induces cognitive impairment in the marmoset.},
  author={A. F. G. Smith and Joanna C. Neill and Brenda Costall},
  journal={Pharmacology, biochemistry, and behavior},
  year={1999},
  volume={63 2},
  pages={201-11}
}
Previous work has shown that dopaminergic systems are involved in cognitive function in the common marmoset. The present study investigated the role of dopamine D3 receptors in cognitive performance in the marmoset. The effects of the putative dopamine D3 receptor agonist, 7-OH-DPAT, on performance of a same-day reversal visual object discrimination task were assessed using a miniature Wisconsin General Test Apparatus (WGTA). Within the same test session marmosets acquired a two-choice object… CONTINUE READING