The dopamine D1D receptor. Cloning and characterization of three pharmacologically distinct D1-like receptors from Gallus domesticus.

@article{Demchyshyn1995TheDD,
  title={The dopamine D1D receptor. Cloning and characterization of three pharmacologically distinct D1-like receptors from Gallus domesticus.},
  author={Lidia Demchyshyn and Kim S. Sugamori and F J Lee and Soheila A Hamadanizadeh and Hyman B. Niznik},
  journal={The Journal of biological chemistry},
  year={1995},
  volume={270 8},
  pages={4005-12}
}
Three genomic clones encoding dopamine D1-like receptors were isolated from the avian species Gallus domesticus. Two of these genes encode proteins of 451 and 488 amino acids, which, based on deduced amino acid sequence identity and homology of exhibited pharmacological profiles, appear to be species homologs of mammalian and vertebrate D1/D1A and D5/D1B receptors, respectively. The third genomic clone, termed D1D, encodes a protein of 445 amino acids displaying a deduced amino acid sequence… CONTINUE READING