The dominant-STN phenomenon in bilateral STN DBS for Parkinson's disease.

  title={The dominant-STN phenomenon in bilateral STN DBS for Parkinson's disease.},
  author={Anna Castrioto and Christopher Meaney and Clement Hamani and Filomena Mazzella and Y Poon and Andres M. Lozano and Mojgan Hodaie and Elena Moro},
  journal={Neurobiology of disease},
  volume={41 1},
In some patients with Parkinson's disease (PD) and bilateral STN-DBS the motor benefit from one STN alone appears similar to the improvement obtained with bilateral STN-DBS. Thus, we hypothesized that some patients have a "dominant-STN," whose stimulation achieves similar results than bilateral stimulation. Twenty-two consecutive PD patients with bilateral STN-DBS were assessed in 4 randomized conditions: bilateral off-stimulation, bilateral on-stimulation, unilateral right- and unilateral left… CONTINUE READING
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