The dog mast cell tumour as a model to study the relationship between angiogenesis, mast cell density and tumour malignancy.

@article{Ranieri2003TheDM,
  title={The dog mast cell tumour as a model to study the relationship between angiogenesis, mast cell density and tumour malignancy.},
  author={Girolamo Ranieri and Letizia Passantino and Rosa Patruno and Giuseppe Passantino and Felicita Jirillo and Annamaria Catino and Vittorio Mattioli and Cosmo Damiano Gadaleta and Domenico Ribatti},
  journal={Oncology reports},
  year={2003},
  volume={10 5},
  pages={1189-93}
}
Substantial experimental data suggest that tumour progression is associated with angiogenesis and that increase in microvessel density (MVD) is associated with increase in mast cells density (MCD). Dog mast cell tumour (MCT) is common in dog with an incidence much higher than that found in human and in both species several common biological and clinical characteristics have been demonstrated. To evaluate the role of angiogenesis in progression of this tumour and to correlate MVD and MCD, in… CONTINUE READING

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