The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering.

@article{Ariel2005TheDP,
  title={The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering.},
  author={A Chialvo Ariel and Pengshuai Li and Wei Wang and Whitney Tang and Gabrielle Fredman and Song Iee Hong and Katherine H. Gotlinger and Charles N Serhan},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 52},
  pages={
          43079-86
        }
}
Docosahexaenoic acid, a major omega-3 fatty acid in human brain, synapses, retina, and other neural tissues, displays beneficial actions in neuronal development, cancer, and inflammatory diseases by mechanisms that remain to be elucidated. In this study we found, using lipid mediator informatics employing liquid chromatography-tandem mass spectrometry, that (10,17S)-docosatriene/neuroprotectin D1, now termed protectin D1 (PD1), is generated from docosahexaenoic acid by T helper type 2-skewed… CONTINUE READING

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