The diversity of sex steroid action: the role of micro-RNAs and FOXO transcription factors in cycling endometrium and cancer.

@article{Lam2012TheDO,
  title={The diversity of sex steroid action: the role of micro-RNAs and FOXO transcription factors in cycling endometrium and cancer.},
  author={Eric W-F Lam and Kunal U. Shah and Jan Joris Brosens},
  journal={The Journal of endocrinology},
  year={2012},
  volume={212 1},
  pages={13-25}
}
The rise and fall in ovarian oestrogen and progesterone production orchestrates a series of events that are indispensable for reproduction, including ovulation, implantation, decidualisation and menstruation. In the uterus, these events involve extensive tissue remodelling, characterised by waves of endometrial cell proliferation, differentiation, recruitment of inflammatory cells, apoptosis, tissue breakdown, menstruation and regeneration. The ability of ovarian hormones to trigger such… CONTINUE READING
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