The diversity of GABAA receptors

@article{Hevers2007TheDO,
  title={The diversity of GABAA receptors},
  author={W. Hevers and H. L{\"u}ddens},
  journal={Molecular Neurobiology},
  year={2007},
  volume={18},
  pages={35-86}
}
The amino acid γ-aminobutyric-acid (GABA) prevails in the CNS as an inhibitory neurotrans-mitter that mediates most of its effects through fast GABA-gated Cl−-channels (GABAAR). Molecular biology uncovered the complex subunit architecture of this receptor channel, in which a pentameric assembly derived from five of at least 17 mammalian subunits, grouped in the six classes α, β, γ, δ, ε, and ρ, permits a vast number of putative receptor isoforms. The subunit composition of a particular receptor… Expand
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