The diverse roles of transverse filaments of synaptonemal complexes in meiosis

@article{Boer2006TheDR,
  title={The diverse roles of transverse filaments of synaptonemal complexes in meiosis},
  author={Esther de Boer and Christa Heyting},
  journal={Chromosoma},
  year={2006},
  volume={115},
  pages={220-234}
}
In most eukaryotes, homologous chromosomes (homologs) are closely apposed during the prophase of the first meiotic division by a ladderlike proteinaceous structure, the synaptonemal complex (SC) [Fawcett, J Biophys Biochem Cytol 2:403–406, 1956; Moses, J Biophys Biochem Cytol 2:215–218, 1956]. SCs consist of two proteinaceous axes, which each support the two sister chromatids of one homolog, and numerous transverse filaments (TFs), which connect the two axes. Organisms that assemble SCs perform… CONTINUE READING

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