The diverse roles of DNA methylation in mammalian development and disease

@article{Greenberg2019TheDR,
  title={The diverse roles of DNA methylation in mammalian development and disease},
  author={Maxim V. C. Greenberg and Deborah Bourc’his},
  journal={Nature Reviews Molecular Cell Biology},
  year={2019},
  volume={20},
  pages={590-607}
}
DNA methylation is of paramount importance for mammalian embryonic development. DNA methylation has numerous functions: it is implicated in the repression of transposons and genes, but is also associated with actively transcribed gene bodies and, in some cases, with gene activation per se. In recent years, sensitive technologies have been developed that allow the interrogation of DNA methylation patterns from a small number of cells. The use of these technologies has greatly improved our… 
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