The diverse functions of the hepatitis B core/capsid protein (HBc) in the viral life cycle: Implications for the development of HBc-targeting antivirals.

@article{Diab2018TheDF,
  title={The diverse functions of the hepatitis B core/capsid protein (HBc) in the viral life cycle: Implications for the development of HBc-targeting antivirals.},
  author={Ahmed K. Diab and Adrien Foca and Fabien Zoulim and David Durantel and Ourania M Andrisani},
  journal={Antiviral research},
  year={2018},
  volume={149},
  pages={
          211-220
        }
}
Virally encoded proteins have evolved to perform multiple functions, and the core protein (HBc) of the hepatitis B virus (HBV) is a perfect example. While HBc is the structural component of the viral nucleocapsid, additional novel functions for the nucleus-localized HBc have recently been described. These results extend for HBc, beyond its structural role… CONTINUE READING