The diverse and pervasive chemistries of the alpha-keto acid dependent enzymes.

@article{Purpero2007TheDA,
  title={The diverse and pervasive chemistries of the alpha-keto acid dependent enzymes.},
  author={Vincent M Purpero and Graham R. Moran},
  journal={Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry},
  year={2007},
  volume={12 5},
  pages={587-601}
}
The number of identified and confirmed alpha-keto acid dependent oxygenases is increasing rapidly. All of these enzymes have a relatively simple liganding arrangement for a single ferrous ion but collectively conduct a highly diverse set of chemistries. While hydroxylations and a variety of oxidation reactions have been most commonly observed, new reactions involving dealkylations, epimerizations and halogenations have recently been discovered. In this minireview we present what is known of the… CONTINUE READING

From This Paper

Topics from this paper.

Similar Papers

Loading similar papers…