The divergent eukaryote Trichomonas vaginalis has an m7G cap methyltransferase capable of a single N2 methylation

@article{SimoesBarbosa2008TheDE,
  title={The divergent eukaryote Trichomonas vaginalis has an m7G cap methyltransferase capable of a single N2 methylation},
  author={A. Simoes-Barbosa and Camila Louly and O. L. Franco and M. A. Rubio and J. Alfonzo and P. Johnson},
  journal={Nucleic Acids Research},
  year={2008},
  volume={36},
  pages={6848 - 6858}
}
Eukaryotic RNAs typically contain 5′ cap structures that have been primarily studied in yeast and metazoa. The only known RNA cap structure in unicellular protists is the unusual Cap4 on Trypanosoma brucei mRNAs. We have found that T. vaginalis mRNAs are protected by a 5′ cap structure, however, contrary to that typical for eukaryotes, T. vaginalis spliceosomal snRNAs lack a cap and may contain 5′ monophophates. The distinctive 2,2,7-trimethylguanosine (TMG) cap structure usually found on… Expand
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