The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat.

@article{Hervieu2000TheDO,
  title={The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat.},
  author={Guillaume J Hervieu and Jane E. Cluderay and David C. Harrison and John Meakin and Peter R. Maycox and Shabina Nasir and Rachel A. Leslie},
  journal={The European journal of neuroscience},
  year={2000},
  volume={12 4},
  pages={1194-216}
}
Melanin-concentrating hormone (MCH), a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus. It is implicated in the control of general arousal and goal-orientated behaviours in mammals, and appears to be a key messenger in the regulation of food intake. An understanding of the biological actions of MCH has been so far hampered by the lack of information about its receptor(s) and their location in the brain. We recently identified the orphan G-protein-coupled receptor SLC-1 as… CONTINUE READING

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