The distribution of the alpha7 nicotinic acetylcholine receptor in healthy aging: An in vivo positron emission tomography study with [18F]ASEM

@article{Coughlin2018TheDO,
  title={The distribution of the alpha7 nicotinic acetylcholine receptor in healthy aging: An in vivo positron emission tomography study with [18F]ASEM},
  author={Jennifer M. Coughlin and Yong Du and Hailey B. Rosenthal and Stephanie Slania and Soo Min Koo and Andrew Park and Ghedem Solomon and Melin Vranesic and Inga Antonsdottir and Caroline L. Speck and Kelly Rootes-Murdy and Alexandria Lerner and Steven P. Rowe and Yuchuan Wang and Wojciech G. Lesniak and Il Minn and Arnold Bakker and Gwenn S. Smith and Robert F. Dannals and Hiroto Kuwabara and Andrew G. Horti and Dean F. Wong and Martin G. Pomper},
  journal={NeuroImage},
  year={2018},
  volume={165},
  pages={118-124}
}
Altered function of the alpha7 nicotinic acetylcholine receptor (α7-nAChR) is implicated in several neuropsychiatric diseases. Nevertheless, studies of the human cerebral α7-nAChR even in healthy aging are limited in number and to postmortem tissue. METHODS The distribution of the cerebral α7-nAChR was estimated in nine brain regions in 25 healthy… CONTINUE READING