The distribution of radioactivity in brains of rats given [N-methyl-11C]PK 11195 in vivo after induction of a cortical ischaemic lesion.

Abstract

PK 11195 is a selective ligand for the peripheral-type benzodiazepine binding site (PTBBS). There are few such sites in normal brain but their number increases in association with tissue necrosis. The time-course of appearance of PTBBS around a focally induced ischaemic lesion in frontal cortex of rat brain was established by autoradiography using [N-methyl… (More)

Topics

Cite this paper

@article{Cremer1992TheDO, title={The distribution of radioactivity in brains of rats given [N-methyl-11C]PK 11195 in vivo after induction of a cortical ischaemic lesion.}, author={Jeroen Cremer and S. P. Hume and Bernadette A M Cullen and R. Myers and L G Manjil and David R. Turton and Soumya Luthra and Devon Bateman and V. W. Pike}, journal={International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology}, year={1992}, volume={19 2}, pages={159-66} }