The distribution of P2X3 purine receptor subunits in the guinea pig enteric nervous system.

@article{Poole2002TheDO,
  title={The distribution of P2X3 purine receptor subunits in the guinea pig enteric nervous system.},
  author={Daniel P Poole and Patricia Castelucci and Heather L. Robbins and Roberto Chiocchetti and John Barton Furness},
  journal={Autonomic neuroscience : basic & clinical},
  year={2002},
  volume={101 1-2},
  pages={39-47}
}
Adenosine 5'-triphosphate (ATP) excites 70-90% of enteric neurons through P2X type purine receptors, and is likely to be an enteric neurotransmitter. Recent studies indicate that the P2X2 subunit is expressed by specific subgroups of enteric neurons, and that there are enteric neurons that are responsive to ATP but lack this subunit. In the present work, we have investigated whether the P2X3 subunit is similarly localised to specific subgroups of neurons, and whether these are different from… CONTINUE READING
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