The distribution-based p-value for the outlier sum in differential gene expression analysis.

@article{Chen2010TheDP,
  title={The distribution-based p-value for the outlier sum in differential gene expression analysis.},
  author={Lin-An Chen and Dung-Tsa Chen and Wenyaw Chan},
  journal={Biometrika},
  year={2010},
  volume={97 1},
  pages={246-253}
}
Outlier sums were proposed by Tibshirani & Hastie (2007) and Wu (2007) for detecting outlier genes where only a small subset of disease samples shows unusually high gene expression, but they did not develop their distributional properties and formal statistical inference. In this study, a new outlier sum for detection of outlier genes is proposed, its… CONTINUE READING