The distribution and metabolism of L-tryptophan in healthy probands under dietary conditions.


Oral administration of 500 mg or 1,500 mg of L-tryptophan (TRP) respectively to healthy probands resulted in a significant increase in free and bound TRP in plasma 2 hours after consumption. Serotonin and 5-hydroxyindole-3-acetic acid (5-HIAA) also demonstrate a significant increase in plasma, while tyrosine shows no changes. However, a competitive… (More)


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