The distribution and fate of 14C-chloramphenicol in the new-born pig.

@article{Appelgren1982TheDA,
  title={The distribution and fate of 14C-chloramphenicol in the new-born pig.},
  author={Lennart Appelgren and Bo Eberhardson and Karin Martin and Premysl Slanina},
  journal={Acta pharmacologica et toxicologica},
  year={1982},
  volume={51 4},
  pages={
          345-50
        }
}
The distribution of 14C-chloramphenicol has been studied in new-born pigs with the aid of whole-body autoradiography. In the lung, liver, adrenal cortex, kidney, myocardium, pancreas, thyroid, spleen and skeletal muscle the amounts of radioactivity were higher than that of the blood short time after injection and remained higher than the blood up to 8 hrs. After 4 and 8 hrs the brain concentration of 14C was also higher than that of the blood. In the bone marrow, however, the concentration did… CONTINUE READING
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