The distribution and density of airway vasoactive intestinal polypeptide (VIP) binding sites in cystic fibrosis and asthma.

@article{Sharma1995TheDA,
  title={The distribution and density of airway vasoactive intestinal polypeptide (VIP) binding sites in cystic fibrosis and asthma.},
  author={Rakhi Sharma and Bruce J. Addis and Peter Key Jeffery},
  journal={Pulmonary pharmacology},
  year={1995},
  volume={8 2-3},
  pages={
          91-6
        }
}
The densities of airway binding sites for Vasoactive intestinal polypeptide (VIP) were determined using 125I-labelled VIP (IVIP) and the technique of autoradiography applied to cryostat sections. Tissue studied included: grossly normal airway tissue taken from lungs resected for bronchial carcinoma (Ca; n = 11) and lungs removed at transplant from patients with cystic fibrosis (CF; n = 7). Lung tissue obtained at post-mortem in cases of fatal asthma (n = 3) or lobes resected for bronchiectasis… CONTINUE READING
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